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Chronic spontaneous urticaria (CSU) is a distressing skin condition that causes red, swollen, itchy and sometimes painful hives or “wheals” on the skin1. At any given time, the worldwide prevalence of CSU is 0.5% to 1%2. Urticaria is defined as chronic when the symptoms spontaneously present and reoccur daily or almost daily for at least six weeks. It is described as spontaneous when symptoms are not triggered by any identified external factor2. Women are twice as likely as men to be diagnosed with the disease and most people first develop symptoms between the ages of 20 and 40.
Sánchez-Borges M, Asero R, Ansotegui IJ, et al. Diagnosis and treatment of urticaria and angioedema: a worldwide perspective (position paper). World Allergy Organization Journal. 2012; 5:125–147 Maurer M, Weller K, Bindslev-Jensen C, et al. Unmet clinical needs in chronic spontaneous urticaria: A GA(2)LEN task force report. Allergy. 2011;66:317–330